解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:A patency capsule (PC) can help predict capsule endoscope (CE) retention; however, PC tolerability is unknown in children. We retrospectively evaluated PC tolerability in school-aged children. METHODS:Sixty-one patients (median age, 12.9 years; range 7.4-17.3 years) who underwent PC examination were analyze...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000477579
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND/AIMS:Acotiamide, a prokinetic drug, is used to treat functional dyspepsia (FD), especially postprandial distress syndrome (PDS). However, a treatment for FD patients with PDS and/or epigastric pain syndrome (EPS) has not been established. We investigated the efficacy of famotidine in combination with acotiam...
journal_title:Digestion
pub_type: 杂志文章,随机对照试验
doi:10.1159/000477345
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Esophageal cancer represents a heterogeneous malignancy mostly diagnosed in advanced stages. Worldwide, squamous cell carcinomas (SCCs) continue to be the most prevalent subtype; however, in the Western countries, the incidence of adenocarcinomas is increasing and will exceed that of SCC in the near future. ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000464130
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND/AIMS:Probiotics appear to improve Helicobacter pylori-associated dyspepsia via an inhibitory effect on H. pylori; however, uncertainty exists regarding their effects in H. pylori-uninfected individuals. We evaluated the efficacy of Lactobacillus gasseri OLL2716 (L. gasseri OLL2716) on H. pylori-uninfected in...
journal_title:Digestion
pub_type: 杂志文章,随机对照试验
doi:10.1159/000479000
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND/AIMS:In patients with active ulcerative colitis (UC), pharmacologics, although initially effective in most patients, are associated with refractoriness, loss of response or unfavourable side effects as additional morbidity factors. Depletion of myeloid lineage leucocytes like the CD14(+)CD16(+) monocyte phen...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000479502
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Since resistance of Helicobacter pylori is developing very fast all over the world, new treatment regimens for eradication are urgently needed. AIM:To compare eradication success rate of H. pylori treatment regimens with and without doxycycline. METHODS:English medical literature searches were conducted fo...
journal_title:Digestion
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000443683
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND/AIMS:This study aimed at (i) clarifying the factors associated with high scores on the modified frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) among 3,505 relatively healthy subjects undergoing routine medical health checkups with gastrointestinal endoscopy and (ii) comparing risk...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000445713
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND/AIM:What naturally happens to patients after they undergo conservative and endoscopic treatment of colonic diverticular bleeding (CDB) is largely unknown. We retrospectively track the long-term outcome of the recurrence of CDB between patients with endoscopic and conservative treatment. METHODS:The group wa...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000452301
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND/AIMS:The benefits of colonoscopy in reducing colorectal cancer (CRC) risk for patients over 75 years are controversial. We aimed to determine whether colonoscopy use is associated with a decreased risk of CRC in patients 76-85 years old in the United States (US). PATIENTS AND METHODS:All patients in the Med...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000442571
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND/AIMS:Colorectal cancer (CRC) patients are at high risk for developing extracolorectal malignancies (EMs). Although development of a second primary cancer and deaths thereof are included as events of disease-free survival (DFS) and overall survival (OS), the role of EMs in these survival end points has not be...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000449132
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:There are unexpectedly large differences between the incidences of acute pancreatitis (AP) as indicated by different hospitals. Retrospective studies suggest that the reason behind this is the large differences that exist between the local managements of abdominal pain at emergency units. Unfortunately, no e...
journal_title:Digestion
pub_type: 杂志文章,多中心研究
doi:10.1159/000441352
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a median 5-year survival of <8%. At the time of diagnosis, a vast majority of pancreatic cancer patients were found to be with either metastatic spread of the disease or locally advanced tumors. Despite relatively low efficacy, ge...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000447739
更新日期:2016-01-01 00:00:00
abstract::The core symposiums of the Japanese Gastroenterological Association (JGA) annual scientific meetings focus on similar topics from year to year. The main topics of these symposiums for the last 3 years were centered on progress in new diagnostics and therapeutic strategies for gastrointestinal malignancy, with a specia...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000368762
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND/AIMS:Only the depth of submucosal invasion can be estimated prior to determining the indications for endoscopic submucosal dissection (ESD) as a curative treatment for colorectal carcinoma (CRC). Here we evaluated the outcomes of ESD for clinical T1 CRCs. METHODS:Of 660 patients who underwent ESD for CRC at...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000368866
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The combined effects of nutrient malabsorption and adiposity on vitamin D status are unclear in pediatric malabsorption syndromes. AIM:To determine the relationship between adiposity and serum 25-hydroxyvitamin D (25(OH)D) in malabsorption disorders. METHODS:Prepubertal children of ages 3-12 with either la...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000381895
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND/AIMS:To identify the number and potential causes of unnecessary diagnostic procedures in a cohort of patients with autoimmune pancreatitis (AIP). METHODS:All AIP cases at our centre between April 2006 and April 2013 were collected and followed up. Diagnosis was established by the International Consensus Dia...
journal_title:Digestion
pub_type: 临床试验,杂志文章
doi:10.1159/000437259
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND/AIMS:This study investigated the safety of endoscopic variceal ligation (EVL) under conscious sedation with midazolam and sequential flumazenil after procedure in these patients. METHODS:A total of 279 patients who underwent secondary prophylactic EVL at our institution between April 2012 and June 2014, wer...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000440715
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Fecal lactoferrin has been introduced as a useful tool for the diagnosis and monitoring of inflammatory bowel disease (IBD). The aim of this study was to assess if fecal lactoferrin can be employed to predict or estimate the effect of granulocyte and monocyte adsorptive apheresis (GMA) in ulcerative colitis ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000375301
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Cholangiocarcinoma (CCA) is the most common hepatobiliary malignancy complicating primary sclerosing cholangitis (PSC). Unfortunately, timely diagnosis of CCA in PSC patients remains challenging. AIM:To investigate the strategies among liver centers regarding pre-transplant screening for CCA in patients wit...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000357445
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND/AIMS:This study aimed to analyze the endoscopic mucosal resection (EMR) with a novel uniquely shaped, double-loop snare (Dualoop, Medico's Hirata Inc., Tokyo, Japan) for colorectal polyps. METHODS:This was a clinical trial conducted in two referral centers, Kyoto Prefectural University of Medicine and Natio...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000368044
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to evaluate the frequency of anatomic variations of the hepatic duct bifurcation using magnetic resonance cholangiopancreatography (MRCP). METHODS:A total of 1,160 consecutive patients, referred to our department for MRCP due to suspected pancreatobiliary disease or before liver tra...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000358558
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND/AIMS:It has been demonstrated that cryptogenic pyogenic liver abscess (PLA) is associated with colonic mucosal defect, especially colorectal cancer (CRC). Therefore, the screening of CRC in patients with cryptogenic PLA is important. This study was to investigate whether computed tomographic colonography (CT...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000356534
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Gut microbiota affects host homeostasis and dysbiosis causes host diseases. Therefore, uncovering the sensing mechanism of bacterial metabolites such as short-chain fatty acid (SCFA) may help us to understand the host-microbiota interaction both in physiological and nonphysiological conditions. SUMMARY:The ...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000356211
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND/AIMS:We evaluated the diagnostic variability and reproducibility of endoscopic signs in two populations with a different pretest likelihood of celiac disease (CD). METHODS:We recruited 289 CD patients (both adults and children) in a multicenter prospective study. Group 1 (high risk) included 111 patients re...
journal_title:Digestion
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1159/000350436
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Upper gastrointestinal bleeding (UGB) is an important precipitating factor for the development of hepatic encephalopathy (HE) in cirrhotic patients. The aim of this study was to evaluate the efficacy of lactulose in a controlled randomized trial for prophylaxis of HE after UGB. PATIENTS AND METHODS...
journal_title:Digestion
pub_type: 杂志文章,随机对照试验
doi:10.1159/000346083
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND/AIMS:Roux-en-Y gastric bypass surgery is the most common bariatric surgery worldwide. We have described thiamine deficiency in patients with small intestinal bacterial overgrowth after gastric bypass. We hypothesized that symptoms of thiamine deficiency are common after gastric bypass. The aims of this study...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000353245
更新日期:2013-01-01 00:00:00
abstract:AIM:To determine the long-term effect of argon plasma coagulation (APC) of gastric inlet patches in the cervical esophagus for patients suffering from globus sensation. METHODS:We intended to follow up all patients between 2004 and 2011 (n = 49) who received argon plasma ablation of gastric inlet patches for globus se...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000355274
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND/AIM:The aim of this study was to examine the relationship between narrow-band imaging (NBI) magnifying observation using the surface pattern as the main evaluation criterion and pit pattern diagnosis on the basis of magnifying observation using a dye in relation to the characteristics of colorectal tumors ac...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000343940
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Previous research has shown that infliximab (IFX) is effective in the management of moderate to severe active ulcerative colitis (UC). Latin American studies are lacking. AIM:To evaluate the efficacy of IFX treatment (including corticosteroid withdrawal, complete mucosal healing, colectomy and hospitalizati...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000355529
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The exact etiology of irritable bowel syndrome (IBS) remains unclear. Curative treatment is not available and current treatment modalities are mainly directed against the predominant symptoms. There are a few studies reporting the beneficial effects of transcutaneous electrical stimulation in patients with c...
journal_title:Digestion
pub_type: 杂志文章,随机对照试验
doi:10.1159/000338301
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIMS:Endoscopic definitions and management of Barrett's esophagus vary widely among countries. To examine the current situation regarding diagnosis, epidemiology, management and treatment of Barrett's esophagus in East Asian countries using a questionnaire-based survey. METHODS:Representative members of the...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000339778
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the effects of proton pump inhibitors on symptomatic inflammatory esophagogastric polyps (IEPs) in a pediatric cohort and to determine the optimal duration of treatment. METHODS:The 11 patients with IEPs were managed with lansoprazole. Follow-up endoscopies were perf...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000327909
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Endoscopic submucosal dissection (ESD) has become the standard endoscopic treatment for early gastric cancer without lymph node metastasis. At present, undifferentiated type intramucosal cancers without ulcer findings <20 mm in size are often chosen as endoscopic treatment lesions for expanded indication. Th...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000334681
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Current treatment strategies of variceal bleeding (VB) include banding and sclerotherapy. However, up to 10% of bleeding events remain refractory to standard therapy with high mortality. With this study, we aimed to evaluate the implantation of self-expanding metal stents (SEMS) for the management o...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000335081
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Medical therapy of inflammatory bowel disease (IBD) is becoming more complex, given the increasing choice of drugs to treat Crohn's disease (CD) and ulcerative colitis (UC). We aimed to summarize the current guidelines for first-line treatments in IBD. METHODS:An extensive literature search with fo...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000341951
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIMS:Defective epithelial barrier has been implicated in the pathogenesis of irritable bowel syndrome (IBS) and inflammatory bowel diseases. The aim of this study was to investigate gut permeability in patients with inactive ulcerative colitis (UC) and in patients with IBS. METHODS:IBS patients of the diarr...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000333083
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIMS:Some minimal changes (MCs) are believed to have a certain relationship with gastroesophageal reflux (GERD). Nonetheless, the individual meaning of MC is still unclear. Our aim was to compare the overall and individual prevalence of MC between patients with non-erosive reflux disease (NERD) and healthy c...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000337198
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIMS:Autoimmune gastritis (AIG) may predispose to gastric carcinoid tumors or adenocarcinomas and may also cause unexplained iron and/or vitamin B(12) deficiency. The aims of this study were to explore clinical manifestations, endoscopic findings and laboratory features of patients with AIG. METHODS:109 pat...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000338295
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIM:Previous studies have reported small intestinal lesions in patients with portal hypertensive disease. However, the etiology of these lesions is not clear, as portal venous pressure was not measured in any of these studies. The aim of this study is to clarify the association between small intestinal lesio...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000338180
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:The present study aimed to evaluate the micronucleus (MN), nucleoplasmic bridges (NPBs) and nuclear buds (NBUDs) in the mitogen-stimulated lymphocytes of patients with ulcerative colitis (UC). In addition, we assessed MN frequency in exfoliated colonic epithelial cells obtained from both the diseased and heal...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000336358
更新日期:2012-01-01 00:00:00